Abstract
Information processing by humans can be biased by their emotions — for example, anxious and depressed people tend to make negative judgements about events and to interpret ambiguous stimuli unfavourably1,2,3,4. Here we show that such a 'pessimistic' response bias can also be measured in rats that are housed in unpredictable conditions5,6. Our findings indicate that cognitive bias can be used as an indicator of affective state in animals, which should facilitate progress in animal-welfare studies.
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References
MacLeod, A. K. & Byrne, A. J. Abnorm. Psychol. 105, 286–289 (1996).
Gotlib, I. H. & Krasnoperova, E. Behav. Therapy 29, 603–617 (1998).
Eysenck, M. W. et al. J. Abnorm. Psychol. 100, 144–150 (1991).
Wright, W. F. & Bower, G. H. Organiz. Behav. Hum. Decis. Process 62, 276–291 (1992).
Willner, P. Psychopharmacology 134, 319–329 (1997).
Zurita, A. et al. Behav. Brain Res. 117, 163–171 (2000).
Nielsen, B. L. Appl. Anim. Behav. Sci. 63, 79–91 (1999).
Fernandes, C. & File, S. E. Pharmacol. Biochem. Behav. 54, 31–40 (1996).
Spruijt, B. M., van den Bos, R. & Pijlman, F. T. A. Appl. Anim. Behav. Sci. 72, 145–171 (2001).
Berridge, K. C. & Robinson, T. E. Trends Neurosci. 26, 507–513 (2003).
Dawkins, M. S. in Coping with Challenge. Welfare in Animals including Humans (ed. Broom, D.M.) 63–76 (Dahlem University Press, Berlin, 2001).
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Harding, E., Paul, E. & Mendl, M. Cognitive bias and affective state. Nature 427, 312 (2004). https://doi.org/10.1038/427312a
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DOI: https://doi.org/10.1038/427312a
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