Table 4 Accuracy of contamination estimates on a simulated early modern human with double-stranded deamination patterns and high present-day modern human contamination. Three cores were used for every program. The programs contamMix and contDeam estimate contamination on a per fragment basis while mtCont estimates contamination on a per nucleotide basis. The contamination on a per nucleotide basis is higher due to the longer average length of contaminating fragments
From: Schmutzi: estimation of contamination and endogenous mitochondrial consensus calling for ancient DNA
Contamination | Contamination | Run time |
---|---|---|
estimate | estimate | |
method | ||
Target contamination rate: 50 % (fragment basis) | ||
contamMix 1.0-10 | 54.9±0.7 % | 4 days |
Schmutzi (contDeam) | 49.0±0.5 % | 68 s |
Target contamination rate: 58.2 % (nucleotide basis) | ||
Schmutzi (mtCont without the predicted contaminant) | 32.0±1.0 % | 183 m |
Schmutzi (mtCont with the predicted contaminant) | 60.0±1.0 % | 200 m |