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  1. Article
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    High Hcy regulates fluid shear stress pathway activity through histone H3K79 homocysteinylation in hyperhomocysteinemia-related child hypertension

    Background

    The rise of hypertension in children has been increasingly associated with hyperhomocysteinemia (HHcy), which is recognized as a major risk...

    Baoling Bai, Lingyun Liu, ... Qin Zhang in Journal of Translational Medicine
    09 May 2025 Open access
  2. Article
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    Comparison of oscillatory activity in substantia nigra pars reticulata between Parkinson’s disease and dystonia

    Parkinson’s disease (PD) is associated with disrupted neural activity in the substantia nigra, but its electrophysiological changes remain...

    Lin Shi, Yichen Xu, ... Anchao Yang in npj Parkinson's Disease
    05 May 2025 Open access
  3. Article
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    A four-state reverse current active fault diagnosis method for cascaded H-bridge multilevel inverter

    Multilevel inverters are prospective in high-voltage and high-power applications because of their low harmonics and high efficiency. Open-circuit...

    Shixin Huang, Yunjie Tang, ... Xuefang Lin-Shi in Electrical Engineering
    05 May 2025
  4. Article
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    Applications of Carbon-Based Multivariable Chemical Sensors for Analyte Recognition

    Over recent decades, carbon-based chemical sensor technologies have advanced significantly. Nevertheless, significant opportunities persist for...

    Lin Shi, Jian Song, ... Jianhua Zhang in Nano-Micro Letters
    03 May 2025 Open access
  5. Article
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    The impact of decreased SIRT1 levels on pediatric primary hypertension and left ventricular hypertrophy: a case-control study

    Background

    Decreased SIRT1 exhibits a correlation with a range of cardiovascular diseases. However, the changes in serum SIRT1 levels in pediatric...

    Yuting Wang, Yao Lin, ... Lin Shi in BMC Pediatrics
    30 April 2025 Open access
  6. Article
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    Investigating the association between polyunsaturated fatty acids and osteomyelitis by Mendelian randomization

    Osteomyelitis, characterized by bone inflammation and infection, poses a significant global health burden. This Mendelian randomization (MR) study...

    Baixing Chen, Bin Pu, ... Hang Dong in Scientific Reports
    28 April 2025 Open access
  7. Article
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    Renal artery branch stenosis induced hypertension in children: a case series

    Purpose

    Renal artery branch stenosis induced hypertension (HTN) in children is rare and facing a great challenge in diagnosis and treatment. This...

    Hongwei Zhang, Yao Lin, ... Lin Shi in BMC Pediatrics
    17 April 2025 Open access
  8. Article
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    FTO controls CD8+ T cell survival and effector response by modulating m6A methylation of Fas

    Functional CD8 + T cell immunity is essential for immune surveillance and host defense against infection and tumors. Epigenetic mechanisms,...

    Lina Sun, Tianzhe Zhang, ... Baojun Zhang in Cell Death & Disease
    15 April 2025 Open access
  9. Article
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    Scalp block improves electrophysiological stability and patient cooperation during deep brain stimulation surgery

    Deep Brain Stimulation (DBS) is a critical intervention for various neurological disorders. While effective, the traditional local infiltration...

    Sining Xie, Yan Liu, ... Lin Shi in Scientific Reports
    12 April 2025 Open access
  10. Article

    Revealing the Oxidative Stress-Related Molecular Characteristics and Potential Therapeutic Targets of Schizophrenia through Integrated Gene Expression Data Analysis

    Schizophrenia is a severe mental disorder characterized by oxidative stress imbalances. The underlying mechanisms of oxidative stress-related gene...

    Xiu-Mei Zhu, Ji Chen, ... Su-Hua Zhang in Molecular Neurobiology
    11 April 2025
  11. Article

    Oral FPR2/ALX modulators tune myeloid cell activity to ameliorate mucosal inflammation in inflammatory bowel disease

    Current treatments of inflammatory bowel disease (IBD) largely depend on anti-inflammatory and immunosuppressive strategies with unacceptable...

    Wen-sheng Yang, Qing Liu, ... Zhi-ping Li in Acta Pharmacologica Sinica
    11 March 2025
  12. Article
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    Diversity of intestinal microbiota and inflammatory cytokines after severe trauma

    Accumulating evidence has reported that the intestinal microbiota could play important roles in the occurrence and progression of severe trauma....

    Chang-qing Liu, Jie Yang, ... Ka Li in Scientific Reports
    07 March 2025 Open access
  13. Article
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    Preliminary experience of combined dual plasma molecular adsorption system and plasma exchange in pediatric acute liver failure: a retrospective case series

    Background

    Pediatric acute liver failure (PALF) is a life-threatening condition with no definitive treatment. This study evaluated the combined use of...

    Jia-Hao Geng, Shi-Lin Liu, ... Shu-Jun Li in BMC Pediatrics
    03 March 2025 Open access
  14. Article

    Multi-interface engineering of FeS2/C/MoS2 with core–shell structure for superior microwave absorption performance

    Heterojunction and morphology control assume a significant part in adjusting the intrinsic electromagnetic properties of absorbers to acquire...

    Pan-Pan Zhou, Cheng-Yao Hu, ... Qi-Tu Zhang in Rare Metals
    03 March 2025
  15. Article
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    Matrix moment approach to positivity bounds and UV reconstruction from IR

    Positivity bounds in effective field theories (EFTs) can be extracted through the moment problem approach, utilizing well-established results from...

    Shi-Lin Wan, Shuang-Yong Zhou in Journal of High Energy Physics
    25 February 2025 Open access
  16. Article

    Experimental and Numerical Study of Multi-Energy Low-Velocity Impact and Compression-After-Impact Damage Mechanism of 3D Woven Composites

    Carbon fiber fabric composites as a multiphase material have excellent mechanical properties such as high specific modulus, stable performance, and...

    Zhiping Ying, Xueyan Sun, ... Lin Shi in Fibers and Polymers
    19 February 2025
  17. Article
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    Pathogenesis of influenza and SARS-CoV-2 co-infection at the extremes of age: decipher the ominous tales of immune vulnerability

    The co-circulation of influenza and SARS-CoV-2 has led to co-infection events, primarily affecting children and older adults, who are at higher risk...

    Kai-lin Mai, Wei-qi Pan, ... Zi-feng Yang in Advanced Biotechnology
    21 January 2025 Open access
  18. Article
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    Coronary health index based on immunoglobulin light chains to assess coronary heart disease risk with machine learning: a diagnostic trial

    Background

    Recent studies suggest a connection between immunoglobulin light chains (IgLCs) and coronary heart disease (CHD). However, current...

    Wenbo Ren, Zichen Zhang, ... Jing Huang in Journal of Translational Medicine
    06 January 2025 Open access
  19. Article
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    Dissecting casual effects of diet on the risk of inflammatory bowel disease and the potential mediation by gut microbiota: a Mendelian randomization study

    Background

    Diet plays a fundamental role in maintaining intestinal health. Here, we investigated whether there is the causal association of diet with...

    Tianqi Liu, Lanqi Zhou, ... Lin Shi in Food, Nutrition and Health
    03 January 2025 Open access
  20. Article
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    Plasma fibronectin is a prognostic biomarker of disability in Parkinson’s disease: a prospective, multicenter cohort study

    In a prospective longitudinal study with 218 Parkinson’s disease (PD) patients in the discovery cohort and 84 in the validation cohort, we aimed to...

    Shuzhen Zhu, Hualin Li, ... Qing Wang in npj Parkinson's Disease
    02 January 2025 Open access
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