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How is this the “first experimental cancer treatment” ?

It’s not. Of course.

It may be the first triple immunotherapy (3 checkpoint inhibitors), given in a neo-adjuvant setting, in glioblastoma.

Still cool, less catchy

(Or maybe I don’t understand “world-first” ?)


The term "world-first" in this context means that this is the first specific cancer treatment of this type:

> It is the first documented use of neoadjuvant triple immunotherapy in glioblastoma

If the headline read "world's first" then it would imply what you understood


We love to debate headlines, don’t we? But along those lines, it seems like they could just say it’s “new” and that would be good enough; a headline doesn’t need to be any more specific.


Let alone Edsger


That reminded me of this classic: https://www.youtube.com/watch?v=icoe0kK8btc


The first link is also watchtwr, but a different post


“This is from August 2000!

Since them, much more detailed magnetic fields maps have been made of the Milk Way: “

I was surprised to see that followed up with link from 2019?


And I now know why you don’t have any auditory disorders


As an anomalous trichromat I would love to see this for red and green as well!


Nervus vagus is X - the tenth cranial nerve


And it was originally the last cranial nerve in vertebrates, before the first spinal nerves have been incorporated in the cranium as the nerves XI and XII.

It and several of the nerves preceding it, which originally innervated the branchial arches, remain different in nature from the following nerves (spinal nerves + cranial nerves XI and XII), whose original main purpose was to innervate the somatic muscles. This difference is more important than whether the nerves happen to exit the central nervous systems between adjacent vertebrae or by holes through the cranium (which are the result of the first vertebrae becoming fused to the occipital bone).

The nervus vagus and its associated ganglia of the vertebrates has a correspondent in the nervous system of most animals, including the arthropods, as a vegetative nervous system of the gastro-intestinal tract, which is connected to the central nervous system from the head, e.g. with the tritocerebrum of the arthropods.


This is why I like HN


Thank you, I needed a consult on that one (but now cannot edit/correct it):

You are correct, Vagus is TENTH Cranial Nerve.


tinypng.com compresses ‘lossless’ .pngs


yeah, but you don’t spot albino’celot

</I’ll show myself out>


"Never use random IVs with GCM; this breaks the authentication"

Why could one not use Encrypt-then-HMAC and HMAC-then-Decrypt with a random IV ?

(Serious question. It definitely sounds like you know what you are talking about, I just can't see what I am missing here)


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