While I'm a proponent, research has made a fairly solid case for THC's ability to trigger latent psychological illness. As you stated, making informed choices relative to your medical history is both critical and necessary to avoid unintended permanent consequences.

It's interesting how vastly different everyone's qualitative experiences are when the physiological states are fairly uniform... I think observing those altered processes with next-gen EEG tech may offer some illumination in our current, limited model of neuroplasticity.