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Aspartame and formaldehyde (whatdoesthesciencesay.wordpress.com)
14 points by ecaradec on June 14, 2010 | hide | past | favorite | 39 comments



I rely heavily on aspartame-filled drinks because I have rejected most other drinks as not suitable to drink throughout a working day.

I've attempted to drink normal sugar-filled soft drinks and felt terrible after a few days. That's based on 3 cans a day. The amount of sugar is just too much for me to handle.

I can drink water, but it is quite boring. I actually find drinking just water stops quenching my thirst and my mouth dries out progressively. Drinking fruit juice is also not going to work as it is very acidic, and I just can't handle more than a couple of glasses.

A mix of these drinks is fine, but not ideal. I just want a constant I can drink without preparatiog.

Diet soda fits all the criteria for me. It has a taste, unlike water, contains caffeine (diet coke is my poison), and rehydrates. I can also drink it all day without any real side-effects. The downside being the aspartame and phenylalnine it contains which may or may not be an issue depending on what you read.

I do limit myself to 3 cans per day, but then aspartame is contained in other things I consume every day. The most frequent of which is sugar free gum.

If there are any alternatives to aspartame-using diet drinks, sugar filled drinks, or just plain water I should be trying I'd appreciate some suggestions.


You should get rid of the sugary and aspartame filled drinks alltogether. Also fruit juice is bad as it has no fiber anymore and will just make you obese. Sugar based stuff just gives you a "high" and the aspartame stuff is really disputed.

There is really nothing wrong with water or tea. Try especially a nice green tea or some other good chinese flavors.

If you must how about use stevia in low amounts for sweetening. It is also not without issues but time has shown that is ok when not consumed overly.


* You should get rid of [...] aspartame filled drinks alltogether.*

But, why?

Except for a few periods of a few months, when I chose to go off caffeine or limited my intake for other reasons, I've been drinking several liters a day of aspartame-and-caffeine-containing drinks since 1996. I've yet to identify any related effects: my teeth aren't great, but haven't been eaten away by acid; I'm overweight, but less than I have been at times since 1990; I don't find dehydration to be a problem. Some of my friends drink similarly large quantities, and none of them have shown any apparent effects, either. This, of course, is mere anecdote, but surely if there were really a serious problem then there'd be an epidemic of some problem easily traced to aspartame, given that millions of people drink liters per day of diet colas and other drinks?


While I agree completely with what you are saying the one thing we don't know about is long term effects. When I say long term I mean drinking several litres a week consistently from age 15-60.

As I am falling into that category (so far drinking diet soda regularly from 16-32 with no noticeable side effects) I do wonder what, if any, problems may come about in later life due to aspartame intake.

I sigh a bit with relief when I read these articles debunking the claims of how bad this stuff is for you. But the doubt still nags at me that there is something not right about taking in so much of this stuff. But then I have the same doubts about too much sugar intake.


isn't it ironic that someone is being upvoted for warning against aspartame drinks on an article debunking any negative effects of aspartame? If there are no safety concerns from the breakdown and there are no calories in it then could you summarise your reasons for the advice?

The main reasons to avoid sugar from reading I've done in the past are to do with insulin spiking which is indeed a very bad issue, though eating polished rice (white rice), bread etc are all just as bad for that (bread is worse as it also contains sugars). Negative effects on teeth being attributed to sugars are largely false and are more to do with the acidity of the carbonated water used.


I quit drinking soda a few years ago, and instead switched to carbonated mineral water. Recently, I bought a soda stream and make my own instad. Just carbonate tap water, add some concentrated flavour, and there you have something that isn't as boring as plain water. A can of CO2 lasts about a month, and it's so nice not to have to carry all that damn drink home everytime you shop.


Please be careful with the plastic bottle, after some time it will contain alot of bacteria if you don't wash it properly.


Excellent tip, carbonated water with a little flavouring may be a nice alternative.


I'm in the same boat. Right now I drink diet soda with aspartame (max 2 cans per day) but I'm not convinced it is without risk. I try to avoid HFCS as well as limit my sugar intake.

I've done a bit of research on various sweeteners and have been trying to find the "perfect drink" but so far, no luck. I want something fizzy and sweet with caffeine but not sweetened using HFCS, sucralose, aspartame, etc.

I use powdered stevia on my cereal and in my tea. There is a soda out there sweetened with stevia but the cost is prohibitive. I have mostly replaced coffee with hot tea and will drink iced tea once in a while but the hassle is usually not worth it to me. Same with the carbonated water mixed with syrup route. Sparkling water does not taste good on its own.

For now, I guess I'll stick with Diet Sunkist until something better comes along.


I find cinnamon tea (with no actual tea) to be quite tasty.

http://www.marksdailyapple.com/health-benefits-cinnamon/


OK this study has some perspective to aspartame converting to formaldehyde.

But what about the excitotoxic effects? I've heard aspartame excites nerve cells in the brain in unusually increased levels which eventually causes the cells to burst and die. How about the truth on that?


I touched a bit on excitotoxins in the article, but decided to leave that for another one if there was enough interest. The major issue is that the biggest proponent of the excitotxin theory is Blaylock (based on some initial ideas from JW Olney). I do not see Blaylock as being at all credible and it was actually during the research for the article that I first stumbled on upon that idea.

By far most people are worried about the formaldehyde and mood/headache effects, so that's what I ended up reducing the article to.


Read the whole article.


Probably not. Human and animal tests have been conducted with enormous doses and no obvious brain damage turned up. It does cause neurological changes, including migraines, in some people, but that is probably because the molecule resembles several neurotransmitters. That's quite common with molecules that resemble neurotransmitters.


Diet coke is almost or just as acidic as regular coke. It will erode your teeth. Unfortunately, definitely not something you can drink all day without any real side-effects.


Neither coke or diet coke will erode your teeth:

http://www.snopes.com/cokelore/tooth.asp


(Sorry, I only now saw your response). Of course coke will not erode your teeth overnight, but I never said that. It will cause dental erosion though, irreversible loss of tooth caused mostly by drinking acidic drinks like soda and apple juice. The Snopes article is too optimistic about the protective effects of enamel and saliva. See (the references at) http://en.wikipedia.org/wiki/Acid_erosion


Rooibos tea?


What about cold drinks? Tea is fine, but I would also like a cold drink alternative.


Ice tea?

Actually simply making a large pot of tea and then cool it and put it into the fridge for some time results in a very nice drink.


thanks tomjen3, I may give that a try


You should not drink so much aspartame drinks on such regular basis.

The biggest reason is it is unnatural material that your body is not used to. These people who study the effects are mere scientists. They have no way to know how your genetically evolved body processes things at a detailed level, they can only look at it at one tiny narrow perspective. To be safe its generally best to avoid unnatural food and drinks completely.


The biggest reason is it is unnatural material that your body is not used to.

Irrelevant, our bodies are capable of handling quite a lot.

These people who study the effects are mere scientists.

And the only people qualified to study these effects are then... what? High priests? Quacks? Astrologers?

They have no way to know how your genetically evolved body processes things at a detailed level, they can only look at it at one tiny narrow perspective.

Uh, science has mapped the biochemical pathways of a lot of substances, and science learns more each day.

To be safe its generally best to avoid unnatural food and drinks completely.

How about perfectly natural toxins, then? Should we avoid those? Or are they safe because they are "natural"?

To argue that something is natural or unnatural is a sure sign that you don't really know what you're talking about.


You are missing my point. I specifically said food and drinks. Lets define natural if you find it vague. I call it natural when it is within the normal diet of humans throughout their evolution. I am not talking about natural mercury being good to your health, for example. That was pretty clear.

You can simply answer this, is it in human's natural diet to have lots of aspartame intake each day?

Furthermore, you are overestimating the power of science. If you think humans have the power of understanding human body so well in a mere 200 - 300 years of scientific past, in comparison to the millions of years of evolution complexity, and the complexity of living organism, you are disillusioned by a great magnitude - that would be a godly power if it was true. I am all with science, and great scientists know to value their experiments humbly.

All I am saying is avoid irregular diets for full safety since humans can't know for sure with narrow angled experiments.


I call it natural when it is within the normal diet of humans throughout their evolution.

Most of the food we eat every day today has not been part of the normal diet of humans throughout our evolution.The vegetables, the fruits, and the animals we eat have been bred and refined and genetically modified, and most are less than a few hundred years old.

You can simply answer this, is it in human's natural diet to have lots of aspartame intake each day?

No, but so what? If scientific consensus says that aspartame is perfectly safe to eat, I'll trust that. I avoid aspartame because I think it tastes like crap. That's a perfectly valid reason not to eat it.

"Because it's not natural and I don't trust those so-called scientists that say it's safe" is right up there with astrology and homeopathy.


Hey, quit with the trolling. Unless that comment is serious, in which case there's no helping you :p


I've heard from people, including my wife, that Aspartame causes cancer. We had a 'discussion' earlier about supplements where I argued that I wouldn't spend money on anything that didn't have scientific studies to show a statistically significant impact by the supplement.

It really bothers me when people trust more in word-of-mouth than they do in science.


My problem with the Aspartame studies is that the control group on average lived for a shorter duration. The test group always lived longer so without dying of heart disease the next prime killer is cancer.

I have yet to see a fixed time limit test (IE when the first mouse dies, kill them all and do the autopsies rather than wait for them to drop one by one). If Aspartame causes cancer it should be significantly visible in the subject animals. However they're living longer and dying of naturally occurring cancers, IIRC one study gave a 20% increase in longevity in the test group that was being fed ridiculous quantities of aspartame (equivalent to pounds a day for humans) but this was never mentioned or pointed out as being a relevant variable.


> It really bothers me when people trust more in word-of-mouth than they do in science.

Me too. Still I have some sympathy for them, because science is not on-off type of thing. You can't just research if particular substance is safe or dangerous. You must know what you are searching for. You must figure out a level for "safe exposure". Thus it can take long time (even decades) before substance x is found and agreed to be harmful. Considering the history of human evolution and huge changes in our diet and chemical environment in the last 50 years, it's perfectly acceptable to be skeptical, until proven otherwise. Bisphenol A makes good example.


This reminds me of Paracelsus famous quote. "All things are poison and nothing is without poison, only the dose permits something not to be poisonous."


Allow me to quote at length from ET Jaynes' book, "Probability: The Logic of Science."

> A common error, when judging the effects of radioactivity or the toxicity of some substance, is to assume a linear response model without threshold (that is, without a dose rate below which there is no ill e ect). Presumably there is no threshold effect for cumulative poisons like heavy metal ions (mercury, lead), which are eliminated only very slowly if at all.

> But for virtually every organic substance (such as saccharin or cyclamates), the existence of a finite metabolic rate means that there must exist a finite threshold dose rate, below which the substance is decomposed, eliminated, or chemically altered so rapidly that it has no ill effects. If this were not true, the human race could never have survived to the present time, in view of all the things we have been eating.

> Indeed, every mouthful of food you and I have ever taken contained many billions of kinds of complex molecules whose structure and physiological effects have never been determined, and many millions of which would be toxic or fatal in large doses. We cannot doubt that we are daily ingesting thousands of substances that are far more dangerous than saccharin, but in amounts that are safe, because they are far below the various thresholds of toxicity. But at present there is hardly any substance except some common drugs, for which we actually know the threshold.


Having Type II Diabetes I probably consume more Aspartame than I should, so it's nice to see misinformation like this debunked. I have talked to other diabetics who have even had physicians warn them about Aspartame. There is so much bad information dominating the SERP's that I prefix all my medical searches with "site:mayoclinic.com"


The problem is that a lot of people worry about their aspartame intake although their diet sucks and they don't exercise at all. Aspartame in this case is your least problem. If you get 90% of your nutrition right, then you can worry about the amounts of aspartame in your soda.

I'm interested in the current state of stevia as it is a real (maybe hyped) alternative sweetener.


Whether or not it has been proven to be unhealthy, I personally feel very strange after consuming even the smallest amount of aspartame. I become nervous and jittery, and feel an odd sensation in my jaw that tempts me to grind my teeth. Others may not have the same symptoms as me, but I steer well clear of anything containing the chemical.


I have mild flu-like symptoms a day after consuming aspartame.

I'd be interested in knowing which of the studies reviewed in the meta study were funded by corporations incentivized by aspartame.


That sounds like caffeine to me!


It happens even when I consume non-caffeinated drinks with aspartame


Then how come I get really bad headaches when eating the stuff, but not with sugar, HFCS, or saccharin?


There's obviously no way for anyone to claim that you specifically don't, but one of the studies I looked at (and there have been others) specifically used patients who believed they got headaches from aspartame. They turned out to be more likely to get one from the placebo control than from aspartame.




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