Speaking of old, cheap medicines that help migraines, much more so imo than many newer expensive medicines, it's definitely worth trying metoclopramide (reglan) or prochlorperazine (compazine).
A lot of docs don't think about using them, because they are cheap, generic and therefore not advertised :)
They shouldn't be taken regularly, they can have nasty side effects if taken regularly, but they are a great drug to use even up to once every week or two weeks to treat an acute severe migraine attack I.e. "rescue medication". Btw, if the migraines are this regular, you should also see a specialist to consider some preventive medication)
My own migraines are pretty mild, but I work as an ER doc, regularly treating patients with migraines that didn't respond to other meds at home.
It's somewhat of a downside and an upside with the medication I take -- it's not a "take it when there's a problem" but a "take it all the time" kind of drug. In this case, because mine were so frequent, I'd be taking them regularly anyway so a daily pill as prevention works really well for me.
My body also has a really bad time with anything that messes with serotonin -- I can't take SSRIs (these are sometimes prescribed for Migraine, but usually as a last resort), I can't take triptans (IANAD, but if I understand it correctly, they're mode of operation is to boost serotonin levels[0]). I've had absolutely no issues on Depokote. The one side effect that it has for me was reducing my anxiety. The crazy thing was that I would have never identified as someone with an anxiety problem, but once I the medicine started working, I noticed that my general outlook on life was a lot more 'calm'.
[0] Or the specific triptan I was on did that as a side-effect ... I discovered this difficulty of mine as a result of getting serotonin shock/syndrom. That was fun!
Do you ever use IV diphenhydramine in the ER when people present with migraine? Last couple times I hit the 48-hour mark and had to go in, I was surprised to get an IV full of Benadryl along with the pain killers.
A lot of docs don't think about using them, because they are cheap, generic and therefore not advertised :)
They shouldn't be taken regularly, they can have nasty side effects if taken regularly, but they are a great drug to use even up to once every week or two weeks to treat an acute severe migraine attack I.e. "rescue medication". Btw, if the migraines are this regular, you should also see a specialist to consider some preventive medication)
My own migraines are pretty mild, but I work as an ER doc, regularly treating patients with migraines that didn't respond to other meds at home.