I think a large number of those drug overdoses are legal drugs that come from big pharma. The abusers of those drugs certainly don't feel anything about the Meican drug trade.
"Analysts pointed to two major reasons for the increase: A growing number of Americans are using opioids, and drugs are becoming more deadly. It is the second factor that most likely explains the bulk of the increased number of overdoses last year."
And they are becoming more deadly because the street drugs are being laced with fentanyl.