Look at the rate of opioid use in the US compared to the rest of the world.

The US consumes about 99% of the world supply of hydrocodone. https://www.washingtonpost.com/news/wonk/wp/2017/03/15/ameri...

These figures are old (2015), but eye-opening.

http://www.painpolicy.wisc.edu/who-regional-office-americas-...

http://www.painpolicy.wisc.edu/sites/default/files/sites/www...

http://www.painpolicy.wisc.edu/sites/default/files/sites/www...

Here's EURO

http://www.painpolicy.wisc.edu/sites/default/files/sites/www...

http://www.painpolicy.wisc.edu/sites/default/files/sites/www...

You can use that site to compare regions. http://www.painpolicy.wisc.edu/explore-data