Not a sufficient amount of profit to be made. Could be lack of sufficient number of customers to offset cost of developing a store (most likely), or zoning and permitting issues making it difficult to obtain the legal rights to open one.

Many people prefer only going to the big stores, such as Target and Costco and other large regional or nationwide companies, so not much room left for independent owners unless they’re in a very dense area where there’s enough people wanting to go to their smaller stores.