Also curious about this - Donner Pass Rd parallels I-80. Beckwourth or Walker passes are lower and less steep, but both add a lot of distance to connect to the I-80/Humboldt River corridor though which seems like the only sane route across Nevada.
Of course there are options to go around both the Sierras and the state of Nevada, Route 66 and up the San Joaquin valley being one example.
Numerous other roadways. For one, Highway 89 and 88 (Monitor Pass and Carson Pass) south of Lake Tahoe, which are both part of the annual Death Ride which I've done a few times. I suppose if I was coming from 50 I'd do 89 (Monitor) and then take 4 (Ebbetts Pass/Pacific Grade) into the Angels Camp area, which is a much nicer ride than 88.
