I have a childhood condition that left me marginally disabled with a bad hip (I probably should get a replacement and I'm not 40 yet) that causes me immense pain some days. I also have life-long mental health issues. I've been 300 pounds and I've lost it via the old-fashioned way - diet and exercise. If I can find ways to make it work, then yes, I do think most anyone can. You do have to try different foods and exercises to see what works for you; every one is different, and in that regard no one can educate you; you have to figure it out for yourself.