From what I've read, since door handles generally are placed in the path of turbulent air that has beed disturbed by the mirrors, it doesn't really make much of a difference.
Most door handles are considerably lower than the mirrors. Door handles are normally several inches down from the window line while mirrors are usually at or above that line.
The Mach E's front door handle things are practically at the window line to take advantage of being in the mirror turbulence area, a handle several inches down probably wouldn't be in it very much.
