I know a few people who have Zscaler deployed at work. It will routinely kick them of the internet, like multiple times a day. It has gotten to the point where they can sort of tell in advance that it's about to happen.
The theory so far it that it's related to their activities, working in DevOps they will sometimes generate "suspicious" traffic patterns which will then trigger someone policy in Zscaler, but they're not actually sure.
ZScaler itself uses port 443 UDP, but blocks QUIC. The last time I checked it didn't support IPv6 so they told customers to disable IPv6. Security software is legacy software out of the box and cuts the performance of computers in half.