Anaconda Code is what you're looking for! It's Python (via PyScript) running as an Excel plug-in, that has full access to the spreadsheet and can harness a big part of the core PyData stack (including matplotlib, sklearn, pandas, etc.)

The whole thing runs via PyScript/WASM, and lives locally inside the Excel spreadsheet. https://www.anaconda.com/blog/introducing-anaconda-code-add-...

Please don't tell people I work with about this.

Arguably, VB6 and Ruby have a pretty similar syntax. And Wasm is first class in the Ruby build farm. https://github.com/ruby/ruby.wasm

Thats mean you want to embed VB code into Browser Like in ActiveX days?

Isn't it the same thing as a SPA or any other WASM? The only real difference now is that it is now accepted and the browsers assist with cross platform APIs (and some security) instead of pure Windows APIs. (Ok, so I made it a bit more simple than it is, but that is how I see it.)

Actually I think Blazor might support class libraries written in VB.NET.

They do and it appears to work really well (I have only experimented with it.)

Oh man that would be so cool. Kinda like the Ruffle Flash player!