AFAIK Fractyl's "drug" is not gene therapy but a surgery where they remove part of the lining of your colon. It is not currently possible (nor will it likely be) to use gene therapy for obesity treatments. The technology is not suitable for this kind of medical application.
Wasn't my understanding from the contact I spoke to at Fractyl and associated docs. Noted to follow up with a ___domain expert, appreciate the context. Are you available for a paid 30-60 min conversation on the topic? Attempting to fill knowledge gaps, as I am not an expert.
slide 5: https://www.fractyl.com/wp-content/uploads/2024/10/DGVS-2024...