One possibility for production use (in case there is a big value) is to split the nodes into one "front" node which requires strong uptime, and a "worker" node which is designed to support rare crashes gracefully, in a way that does not impact the front.

This is what we use at https://transport.data.gouv.fr/ (the French National Access Point for transportation data - more background at https://elixir-lang.org/blog/2021/11/10/embracing-open-data-...).

Note that we're not using Pythonx, but running some memory hungry processes which can sometime take the worker node down.