This is exactly where I'm at now. I honestly don't care about PC upgradability anymore. I buy a new cpu, motherboard, memory and gpu all at once, and I'd be more then happy to just buy it all as one integrated unit. And fan noise is also a BIG deal for me.

Between consoles and macs/macbooks, the writing is on the wall and cpu+cpu+unified memory is the future for performance. I will absolutely be looking at buying one of framework desktops instead of building a new PC soon.