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I'm skeptical of your claim because if there's any additional margin to be made doing it artificially, at big-pharma scale history shows that they plenty willing to squeeze every penny out that they can even if it's less effective/natural.



That's true, but doesn't really squeeze natural alternatives out of the market if they're effective.

For example, there's a prescription engineered version of melatonin.

Melatonin is still a huge business.


Red Yeast rice exists, and so does lovastatin (Altoprev)




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