I have ADHD and caffeine very easily makes me jittery. Ordering my cappuccino 'half-caff' has terrifically improved my life. Stimulant medication, the kind prescribed by the doc, easily makes me jittery, too.

The narrative that 'stimulants calm down people with ADHD but make neurotypicals wired' never sat well with me. But I totally believe that it makes you and many other people calmer without any friction.

There must be a wide range of physiological causes and behavioral circumstances that lead to an ADHD diagnosis, such that people like me take a baby dose of methylphenidate or else I get paradoxically overstimulated and distractible and physically uncomfortable.

Or maybe my stimulant tolerance is unrelated to the ADHD and it's just enzymes. I think I had a flag for one of those SNPs that makes me sensitive to caffeine...

As I said, there are many exceptions. It is just a correlation.

There are people with ADHD for whom meds don't work at all, some for who it works in very low doses, some that need very high doses, everyone is different. Same with reactions to coffein.

Diversity is the norm in nature when talking about individuals. ADHD is super complex and how stimulants work is also super complex and the interactions, well we barely have any idea. It doesn't really say anything about your ADHD that you are more or less sensitive to stimulants other than that your are more and less sensitive to stimulants.

Like you wrote, it could be just some enzymes or whatever. Humans are just crazy complex. It is still useful to talk about fact that a statistically significant subset of people with ADHD react differently to caffeine than most neurotypicals.

For what it is worth, I envy you a lot being more sensitives. I can kill five, six, seven cups of coffee and not feel anything. It sucks.

> Stimulant medication, the kind prescribed by the doc, easily makes me jittery, too.

How do you treat your ADHD then?

I do take a stimulant but it's a lower dose and it's delayed-release in a way that makes it easier to tolerate.

I do.

I think there's another dimension of temporal tolerance to consider.

There have been times in my life where I consumed a lot of caffeine, and it brought on the paradoxical sleepy effect.

And other times where I tried to eliminate caffeine, and a fallen-off-the-wagon strong dose gets me jittery, but acclimation happens in 24-48 hours.