It's not hard to set up nearly fault proof routines and reminders.
For example, I have a pill container for the days of the week. Pills go directly into my pocket and don't come out unless they're going in my mouth (almost always during breakfast.) The pocket to mouth routine makes sure I don't set them down somewhere and the pill box gives proof later that I took them.
Only tangentially related really but almost all of the variance I have ever observed in ability to remember things like this is just trying at all to use a mnemonic or routine.
The above routine is a specific practice to remember something — I basically think it would be effective for anyone that actually did it, and almost all non-adherence would be at step zero.
I'm terrible at remembering to take pills. Maybe it's because they're pretty low stakes?