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> Multiple surgeries is not sustainable. Too much uncertainty

I'm not sure where this is coming from. Multiple cardiac bypasses have a ton of uncertainty, but they are effective because efficacy is measured by quality of life * increased lifespan.

Multiple surgeries (the time it takes to regrow major veins from capillaries that aren't blocked off) to relatively non-lethal parts of the body seems very sustainable for a human lifespan after 60 or 55 or whatever.






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