MDMA is not safe at all for rec use. It’s known to lesion the serotonergic system, even with a single dose. HED is always hard but if you compare the rat dosage they used with a typical 6-7x adjustment I think it comes in at not 150mg ish for a 175lb adult. Not that high relative to common dosing, especially if you’re a 98lb rave chick not a 175lb male.
Now factor in how hard it is to actually dose and the possible inclusion of other amphetamine analogs. Eg I’ve heard of para-chloro(meth)amphetamine showing up a few times, which is used intentionally as a neurotoxin to permanently destroy neurons.
And of course you have dysregulation of the brain’s temperature, magnified by the hot and high-cardio environments where MDMA is usually taken, which can be additionally neurotoxic.
If you synthesize your own or know someone who can, your risk is lower, but MDMA is simply not a safe thing to take.
Now factor in how hard it is to actually dose and the possible inclusion of other amphetamine analogs. Eg I’ve heard of para-chloro(meth)amphetamine showing up a few times, which is used intentionally as a neurotoxin to permanently destroy neurons.
And of course you have dysregulation of the brain’s temperature, magnified by the hot and high-cardio environments where MDMA is usually taken, which can be additionally neurotoxic.
If you synthesize your own or know someone who can, your risk is lower, but MDMA is simply not a safe thing to take.