The commuter busses in NYC don't have bathrooms. For instance the X1 bus goes 45 minutes non-stop:

Schedule: http://www.mta.info/nyct/bus/schedule/xpress/x001cur.pdf

I visited my friend in New York, and he took the express from Staten Island to Manhattan, and it was ~45 minutes without any stops (from the last Staten Island one to the first Manhattan one)

Taxi rides, flights, buses all have 30 min rides FREQUENTLY and no washroom facilities in those 30 min.