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Perhaps you didn't spend very much time reading the site, but Galaxy isn't cloud only, you can host it yourself.

https://wiki.galaxyproject.org/Admin/GetGalaxy

As for the project, I am very interested in seeing how well they do file manipulation and data handling. My non-compete in the bioinformatics field is almost up, and I would love to find an open source project to latch onto and help.

Also, when it comes to bioinformatics, I would say control of data (especially in research settings) is of paramount importance, so you hit the nail on the head with that one. I don't think it will be much of an issue though, simply because the kind of data sizes you have to deal with to do good analysis is so huge that doing it on a cloud service simply isn't feasible unless you have a massively fat internet pipe to use.




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